Detecting virus signatures is so last year. Creating a virus with a unique signature or hash is quite literally child’s play, and most anti-virus products catch just a few percent of the malware that is active these days. You need better tools, called endpoint detection and response (EDR), such as those that integrate with SIEMs, that can recognize errant behavior and remediate endpoints quickly.
I like to think about EDR products in terms of hunting and gathering. You can read more in my post in EventTracker’s blog this week here.